Skin Quality Enhancement Injectables

Advanced Aesthetics » Face » Skin Quality Enhancement Injectables

Glowing, healthy skin is the foundation of a refreshed appearance. Our skin quality enhancement treatments, including Polynucleotides and Profhilo, promote collagen, hydration and firmness, visibly improving the texture and tone of your skin.

Skin Quality Enhancement Injectables:

Polynucleotide Rejuvenation


A regenerative boost for tired, damaged or ageing skin, designed to heal from within and reveal a naturally revitalised complexion.

  • If your skin is showing signs of fatigue, dehydration, or early ageing, such as fine lines, dullness, loss of elasticity or scarring, polynucleotide injections offer a gentle yet powerful solution.

    This treatment is ideal for those looking to improve texture, tone, and radiance without adding volume or changing facial structure. It’s also perfect for preparing the skin ahead of other aesthetic procedures.

  • Polynucleotides are naturally derived molecules found in DNA that support cell regeneration and skin repair. Injected into the skin, they activate fibroblasts and stem cells to boost collagen production, deeply hydrate, and neutralise free radicals, restoring the skin’s elasticity, brightness, and health over time.

    This treatment is especially effective for:

    • Smoothing shallow wrinkles

    • Improving skin quality and hydration

    • Reducing the appearance of scarring

    • Enhancing delicate areas like the neck, décolleté, and under-eyes

    • Preparing the skin for lasers or other aesthetic procedures

  • TAfter assessing your skin, your practitioner will select the appropriate formulation (PDRN Medium or Strong). Your skin is then cleansed and a topical numbing cream may be applied.

    Using either microinjections or a cannula, the polynucleotide solution is gently administered into targeted areas. The procedure typically lasts 20–40 minutes and is well-tolerated, with minimal discomfort.

    Mild redness or swelling may occur post-treatment but usually fades within hours. No significant downtime is required.

  • Initial improvements in hydration and skin texture may be visible shortly after treatment. However, the real transformation unfolds over several weeks, as new collagen forms and cellular repair is activated.

    Skin becomes visibly firmer, smoother, and more radiant, with optimal results appearing 6–8 weeks after your first session. A course of treatments is often recommended for cumulative and longer-lasting benefits.

Profhilo Skin Remodelling


A gentle yet powerful injectable that deeply hydrates and rejuvenates your skin, leaving you looking naturally refreshed, not “done.”

  • If your skin feels dull, crepey, tired or dehydrated—and you’re noticing a loss of firmness or elasticity—Profhilo is ideal for restoring a youthful glow without adding volume.

    It’s particularly suited for delicate or hard-to-treat areas like the neck, hands, forehead, and décolleté where traditional fillers may be less effective or appropriate.

  • Profhilo is a next-generation injectable treatment that works differently from traditional fillers. It contains a highly concentrated, stabilised form of hyaluronic acid (HA) that spreads smoothly beneath the skin, attracting water and stimulating the production of four types of collagen and elastin.

    Rather than volumising, it remodels and improves skin quality—enhancing hydration, tone, elasticity and firmness from within. The result is skin that looks fresher, tighter and more luminous, without any heaviness or puffiness.

  • Profhilo is administered via small injections into five strategic areas of the face (or other target zones), known as Bio-Aesthetic Points (BAPs). These points are carefully selected for optimal diffusion and natural-looking results.

    The treatment takes around 15–30 minutes. A numbing cream may be applied beforehand, but discomfort is minimal and downtime is very limited—most clients resume their normal activities shortly after.

    The recommended protocol includes two sessions, one month apart.

  • Many clients notice an improvement in skin texture and hydration within a few days of the first session. Over the following weeks, collagen and elastin production are stimulated, leading to visibly firmer, smoother, and more radiant skin.

    For best results, a second treatment is carried out one month later, with ongoing improvements continuing to develop for up to 8 weeks. Maintenance treatments every 6–9 months help sustain results.

Other Non-Invasive Face Treatments