Weight Management Transformation
Our 360 Weight Management Clinic

Your Personalised Weight Management Programme

Comprehensive medical support including lifestyle, diet & exercise prescription, evidence-based weight loss medication (oral or injectables) and referral for bariatric surgeries if needed.

A Hat Trick of Honours for The Ghanem Clinic

Aesthetic Medicine Awards 2025

The Ghanem Clinic team celebrating their triple win
Our team celebrating an unprecedented triple win.

Our Triple Win Recognition

  • Aesthetic Clinic of the Year – London
  • Aesthetic Clinic of the Year – UK
  • Aesthetic Practitioner of the Year – Surgeon Ali Ghanem

The Judges Recognised:

Patient-first approach, excellence in treatments, outstanding standards, and pioneering work in facial rejuvenation.

Dr. Mahmoud Elkhouly
Meet Our Weight Loss Doctor

Dr. Mahmoud Elkhouly

MBChB (Hons.), MRCGP, PGCert MedEd.

  • Qualified GP (NHS & Private)
  • Longevity & Regenerative Medicine Specialist

With over 10 years of medical experience across the UK and abroad, Dr. Mahmoud Elkhouly brings a unique, well-rounded perspective to health and wellbeing. Having trained and worked as a plastic surgery resident before specialising in Family Medicine, he now practices as an NHS and private GP in London.

His clinical focus lies in the intersection of metabolic health, sustainable weight management, hormonal imbalance and longevity — recognising that excess weight and poor lifestyle habits can deeply impact mental, physical, and emotional wellbeing.

Through the clinic, he combines evidence-based medicine, personalised nutrition, and modern longevity practices to help patients achieve lasting results and an improved quality of life.

The Hidden Risks of Excess Weight

Obesity increases the risk of developing various health problems. Even modest weight loss significantly reduces these risks.

Heart & Metabolism

Higher weight creates a linear rise in vascular damage and cardiac strain. It directly drives metabolic collapse, insulin resistance, and liver damage.

  • Stroke Risk: Increases ~40% for every +5 BMI units.
  • Diabetes: BMI ≥ 35 increases risk by 10–20x.
  • Heart Failure: Increases ~30% for every +5 BMI units.
0%

Increase in Stroke Risk (per +5 BMI)

0x Diabetes Risk
0% Fatty Liver (per unit)

Brain & Cognitive Health

Midlife obesity leads to accelerated brain aging and increased dementia burden. Weight gain affects brain structure, vascular supply, and long-term cognitive aging.

  • Dementia: Midlife obesity increases risk by 33–45%.
  • Alzheimer's: Central obesity increases risk by ~3x.
  • Brain Aging: Accelerated by up to 10 years in structural MRI studies.
0%

Higher Dementia Risk

0Years Aged
0x Alzheimer's Risk

Cancer Risk

Obesity is a Group 1 carcinogen linked to >13 cancers. Weight gain fuels hormonal, inflammatory, and insulin-driven cancer pathways.

  • Endometrial Cancer: 60% increase for every +5 BMI units.
  • Breast Cancer: Postmenopausal risk increases 20–50%.
  • Colorectal Cancer: 15% increase for every +5 BMI units.
0+

Cancers Linked to Obesity

Endometrial Risk Increase60%
Breast Cancer Risk Increase50%

Life Expectancy & Fertility

Weight is directly tied to healthy lifespan and survival. It also disrupts hormonal health and sexual wellbeing in both men and women.

  • Infertility: Women with obesity have 3x higher risk.
  • Life Expectancy: Severe obesity shortens life by 6–10 years.
  • Pregnancy: Complications increase by >50%.
0Yrs

Reduction in Life Expectancy

0x Infertility Risk
0% Pregnancy Comp.

Your Journey: Step by Step

We understand weight management is personal. Our structured pathway ensures we treat the root cause, not just the symptoms.

1

Initial Assessment

You'll complete a questionnaire about your health history, existing conditions (like diabetes or thyroid issues), and personal goals. This helps us design a programme specifically for you.

2

Initial Consultation

Your consultation with our functional medicine specialist regarding your risk factors and weight concerns, planning your possible treatment options and investigations.

3

Understanding Your Body

Medical investigations establishing your baseline blood panel, hormonal and nutritional status, cholesterol and more, besides using the gold standard techniques for body composition analysis.

4

Bespoke Treatment Plan

We establish your treatment route: this might vary from one patient to another, including lifestyle approach (exercise & nutrition), weight loss tablets, injectables or referral for bariatric surgeries.

Data-Driven Care

We don't guess. We test.

Advanced Blood Testing

Advanced Blood Testing

Hormones, lipids, & sugars

DEXA Scan

Body Composition

Visceral fat & muscle mass

DNA Testing

DNA Testing

Metabolic genetic insights

Ongoing Support

Ongoing Support

Monitoring 24/7 if needed

Treatment Options

Alongside lifestyle coaching, we offer FDA-approved medical supports.

Rybelsus

Oral Tablet

Daily oral medication for those who prefer tablets over needles.

View Details
Frequency: Daily (Empty Stomach)
Avg Loss (6mo): ~8-10%
Mechanism: Oral GLP-1

Key Benefits: Effective blood sugar control and appetite regulation without injections. Must be taken 30 mins before eating.

Wegovy

Semaglutide Injection

Weekly injection mimicking GLP-1 to regulate appetite.

View Details
Frequency: Once Weekly
Avg Loss (6mo): ~10.9%
Mechanism: GLP-1 Agonist

Key Benefits: Helps regulate appetite and food intake. In clinical studies, nearly one-third of participants lost 20% of their body weight at 12 months.

Mounjaro

Tirzepatide Injection

Dual-action (GIP & GLP-1) weekly injection for enhanced results.

View Details
Frequency: Once Weekly
Avg Loss (6mo): ~12-15%
Mechanism: Dual GIP & GLP-1

Key Benefits: Regulates appetite and improves blood sugar. Some individuals lost over 20% of body weight at 12 months in clinical studies.

We also offer non-invasive procedural options like the Allurion Swallowable Balloon.

Choose Your Programme

6-12 month programmes starting from £700

Essential Reset Program

A streamlined, medically supervised reset for patients who want professional guidance with/without medication. Private prescriptions can be provided separately if medically suitable.

Core Transformation Program

A comprehensive blend of medical consultations, nutrition coaching, blood work and body composition analysis. Ideal for those wanting a structured, guided transformation without medication included.

Premium Elite Metabolic Program

Our most complete programme — medical specialist follow-ups, advanced DEXA scans, body composition analysis, DNA testing, meal plans, and round-the-clock support.

Features & Benefits Essential Reset
Program 		Core Transformation
Program 		Premium Elite
Metabolic Program
Best For Simple metabolic reset with/without medication Structured change with deeper support Full medical, nutritional and metabolic optimisation
Medical Specialist Consults Initial + 3 follow ups Initial + 3 follow ups Initial + 6 follow ups
Private Prescription Access
Blood Tests 2 Tests 2 Tests
Body Composition (DEXA) 2 Scans 2 Scans
1:1 Nutritionist Sessions 3 Sessions 6 Sessions
Nutritional DNA Testing
Bespoke Meal Plans
24/7 WhatsApp Medical Support
Select Essential Select Core Select Elite

Essential Reset

  • Medical Specialist Consults (Initial + 3)
  • Private Prescription Access
  • No Blood Tests
  • No DEXA Scans
  • No Nutritionist Sessions
Select Essential

Core Transformation

Most Popular
  • Medical Specialist Consults (Initial + 3)
  • 2 Blood Tests Included
  • 2 DEXA Body Scans
  • 3 Nutritionist Sessions
  • No DNA Testing
Select Core

Premium Elite

  • Medical Specialist Consults (Initial + 6)
  • 2 Blood Tests Included
  • 2 DEXA Body Scans
  • Nutritional DNA Testing
  • 6 Nutritionist Sessions
  • 24/7 Medical Support
Select Elite
Understanding BMI Classes for Different Ethnicities Understanding BMI Classes for Different Ethnicities

Frequently Asked Questions

How much weight can I expect to lose?
Results vary by individual, but clinical studies on our offered treatments show the following averages:
  • Mounjaro (Tirzepatide): Approximately 12-15% weight loss at 6 months, with some individuals achieving over 20% loss at 12 months.
  • Wegovy (Semaglutide Injection): Approximately 10.9% weight loss at 6 months, with nearly one-third of participants losing 20% by 12 months.
  • Rybelsus (Semaglutide Tablet): Average weight loss of 8-10% over 6-12 months.
  • Lifestyle Only: Generally 5-10% body weight loss within 6 months through diet and exercise alone.
What happens if I don't see results?
We closely monitor your progress. If you do not achieve at least 5% weight loss after 6 months on your chosen plan, we will conduct a full review. This may involve adjusting your medication dosage, switching to an alternative treatment, or discussing procedural interventions such as the Allurion balloon or referrals for bariatric surgery if appropriate.
Are there side effects to the medications?
Yes, like all medications, GLP-1 agonists can cause side effects. The most common are gastrointestinal, including nausea, diarrhea, vomiting, constipation, and abdominal pain. These are typically mild to moderate and subside as your body adjusts. Serious but rarer risks include pancreatitis and gallbladder issues; your doctor will screen for these risks during your initial consultation.
Why should I commit to an 18-month programme?
Obesity is a chronic condition that requires long-term management. While 6 months can yield significant results, an 18-month programme is designed to help you maintain that weight loss, solidify new lifestyle habits, and prevent relapse. It also offers significant financial savings compared to renewing shorter programmes.
Can I take these medications if I have diabetes?
Yes, many of these medications (like Rybelsus and Mounjaro) are also indicated for Type 2 diabetes. However, if you are already taking insulin or sulfonylureas, you must inform your doctor, as combining them may increase the risk of hypoglycemia (low blood sugar). We will adjust your plan accordingly to ensure your safety.

Start Your Journey Today

Contact The Ghanem Clinic for a personalised assessment and discover the medical weight management plan that works for you.

Book Your Assessment Call: +44 20 3750 0400
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